Purified Anti-Human CD19 Antibody[HD37]

CVID, B-lymphocyteantigenCD, B-lymphocyte antigen CD, T-cellsurfaceantigenLeu, Differentiation antigen CD, T-cell surface antigen Leu, B-lymphocytesurfaceantigenB, B-lymphocyte surface antigen B, B4, CVID3, CD19, B-lymphocyteantigenCD19, B-lymphocytesurfaceantigenB4, T-cellsurfaceantigenLeu-12, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12, B4, CVID3, CD19, CD19 molecule

HD37

Rabbit IgG, κ

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FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

CD19 protein is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses . CD19 is expressed throughout B cell development from pre-B cells through mature B cells, and it is commonly used as a B cell lineage marker . It is required for the responsiveness of mature B cell to antigen stimulation, germinal center development, and antibody affinity maturation . The CD19 protein associates with the B cell antigen receptor (BCR), CD81, CD38, CD21, CD22, and IFITM1/CD225/Leu13. These associations enable CD19 to amplify B cell signaling and reduce the threshold for antigen stimulation through the BCR.

CD19

Rabbit

Human

Monoclonal

>98%, Protein A/G purified

FCM

≥ 1 mg/mL

Unconjugated

PBS, pH 7.2. Contains 0.05% proclin 300.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

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