Purified Anti-Human CD20 Antibody[2H7]
- 货号：GF1212A
![Purified Anti-Human CD20 Antibody[2H7]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
| Alternate Names | B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, MS4A1 |
| Clone No | |
| Isotype | Mouse IgG2b, κ |
| Leadtime |
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| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
|
| Background |
CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
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| Immunogen | Recombinant Human CD20 protein |
| Abbre | CD20 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Applications |
FCM
|
| Research Areas | Costimulatory Molecules;Immunology |
| Concentration | ≥ 1 mg/mL |
| Conjugation | Unconjugated |
| Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12个月 |
| Shipping |
Ice bag |
Human peripheral blood lymphocytes were stained with 0.2 μg AF/LE Purified Anti-Human CD20 Antibody[2H7](Right) and 0.2 μg Mouse IgG2b, κ Isotype Control(Left), followed by Alexa Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody, then anti-Human CD19 FITC-conjugated Monoclonal Antibody.
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