Purified Anti-Human CD243 Antibody[15D3]

MDR, PGY, ABC, ABCB, P-glycoprotein, Phospholipid transporter ABCB, ATP-dependent translocase ABCB, ATP-binding cassette sub-family B member, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1, P Glycoprotein, ABCB1, ATP-binding cassette sub-family B member 1, ATP-dependent translocase ABCB1, P-glycoprotein 1, Phospholipid transporter ABCB1, MDR-1,  P-gp,  gp170,  ABC-B1, ATP binding cassette, Colchicin sensitivity, Doxorubicin resistance, member 1, Multidrug resistance 1, Multidrug resistance protein 1, P glycoprotein 1, P gp, sub family B (MDR/TAP)

15D3

Mouse BALB/c IgG1, V-KAPPA

咨询

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. Mutations in this gene are associated with colchicine resistance and Inflammatory bowel disease 13. Alternative splicing and the use of alternative promoters results in multiple transcript variants.

CD243

Mouse

Human

Monoclonal

>98%, Protein A/G purified

FCM

≥ 1 mg/mL

Unconjugated

PBS, pH 7.2. Contains 0.05% proclin 300.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag