Purified Anti-Human CD32 Antibody[IV-3]

IGFR2, CD32, CDw32, FCG2, FCGR2B, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, IgG Fc receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-b

IV-3

Mouse IgG2b, κ

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FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

CD32

Mouse

Human

Monoclonal

>98%, Protein A/G purified

FCM;Block

≥ 1 mg/mL

Unconjugated

PBS, pH 7.2. Contains 0.05% proclin 300.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag