Purified Anti-Human CD3E Antibody[CRIS-7]

IMD, CD3E, IMD18, T3E, TCRE, CD3e molecule, CD3 epsilon, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, T3, CD_antigen: CD3e, epsilon

CRIS-7

Mouse IgG2a, κ

咨询

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

The CD3ε chain of the CD3-TCR complex is a type I membrane protein that undergoes conformational change following ligation of the TCR-CD3 complex. This conformational change leads to exposure of the proline rich sequence in CD3ε and results in recruitment of Nck. It is expressed by all mature T cells and forms a heteromeric complex with CD3 α/β or γ/δ and ζ chains. It is important in T cell development, and deficiency of this gene has been associated with severe immunodeficiency.

CD3E

Mouse

Human

Monoclonal

>98%, Protein A/G purified

FCM

≥ 1 mg/mL

Unconjugated

PBS, pH 7.2. Contains 0.05% proclin 300.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag