Purified Anti-Human CD61 Antibody[VI-PL2]

ITGB, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT, Integrin beta 3, ITGB3, Integrin beta-3,  &, beta-3 integrin-n, beta subunit, CD 61, CD61 antigen, HPA 1, HPA 4, Integrin beta 3 (platelet glycoprotein IIIa antigen CD61), Integrin beta chain beta 3, ITB3, ITG B3, ITGB 3, ITG-B3, NAIT, Platelet fibrinogen receptor, Platelet fibrinogen receptor beta subunit, Platelet glycoprotein IIIa, Platelet glycoprotein IIIa precursor, Platelet Membrane Glycoprotein IIIa, PTP

VI-PL2

Mouse IgG1, κ

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FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.

CD61

Mouse

Human

Monoclonal

>98%, Protein A/G purified

FCM

≥ 1 mg/mL

Unconjugated

PBS, pH 7.2. Contains 0.05% proclin 300.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

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