Purified Anti-Human CD8a Antibody[HIT8a]

CD8,  Leu-2,  Ly-2, CD8, CD8 antigen alpha po, CD8 antigen alpha polypeptide, CD8A, Leu, Leu2, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu, T-lymphocyte differentiation antigen T8/Leu-2, T8, alpha polypeptide (p32), p32

HIT8a

Mouse IgG1, κ

咨询

CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

CD8a

Mouse

Human

Monoclonal

FCM

≥ 1 mg/mL

Unconjugated

PBS, pH 7.2. Contains 0.05% proclin 300.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag