Purified Anti-Human/Mouse CD44 Antibody[IM7]

MDU2,  MDU3,  MIC4, CD44, CD44 antigen, CDw44, Epican, LHR, PGP-1, PGP-I, Phagocytic glycoprotein 1, Phagocytic glycoprotein I

IM7

Rat IgG2b, κ

咨询

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

CD44

P15379, P16070

Rat

Human;Mouse

Monoclonal

>98%, Protein A/G purified

FCM

≥ 1 mg/mL

Unconjugated

PBS, pH 7.2. Contains 0.05% proclin 300.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag