Purified Anti-Mouse CD90.2/Thy1.2 Antibody[30H12]

CD90.2, Thy-1.2, Thy-1.2 antigen, Thy-1.2 membrane glycoprotein, Thy1.2

30H12

Rat IgG2b, κ

咨询

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.

CD90.2/Thy1.2

Rat

Mouse

Monoclonal

>98%, Protein A/G purified

FCM

≥ 1 mg/mL

Unconjugated

PBS, pH 7.2. Contains 0.05% proclin 300.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag