RAC2 Polyclonal Antibody
- 货号：GA402450L
Price:
Size:
100 μL
25 μL
| Verified Samples |
Verified Samples in IHC: Human tonsil |
| Dilution | IHC 1:50-1:200 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Human Ras-related C3 botulinum toxin substrate 2 protien |
| Abbre | RAC2 |
| Synonyms | small GTP binding protein Rac2), EN 7, GX, HSPC 022, HSPC022, RAC 2, Ras related C3 botulinum toxin substrate 2, Ras related C3 botulinum toxin substrate 3, Ras related C3 botulinum toxin substrate 3 (rho family, Rho family small GTP binding protein Rac, p21 Rac 2 |
| Swissprot | |
| Cellular Localization | Cytoplasm |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Background | RAC2,also named as GX,belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses,such as secretory processes,phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome. |
Immunohistochemistry of paraffin-embedded Human Tonsil tissue using RAC2 Polyclonal Antibody at dilution of 1:200
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武汉市高新大道858号光谷生物医药产业园二期B18栋