Recombinant Human CCL27/CTACK Protein(Sumo Tag)

CCL;SCYA;CCL27;ALP;CTACK;CTAK;ESKINE;ILC;PESKY;SCYA27;CC Chemokine ILC;C-C Motif Chemokine 27;Cutaneous T-Cell-Attracting Chemokine;IL-11 R-Alpha-Locus Chemokine;Skinkine;Small-Inducible Cytokine A27;Chemokine (C-C motif) ligand 27;Cutaneous T cell attracting chemokine;IL 11 R alpha locus chemokine;member 27;Small inducible cytokine A27;small inducible cytokine subfamily A (Cys-Cys)

E.coli

Phe25-Gly112

Q9Y4X3

Human

22.6 kDa

28 kDa

N-Sumo

Not validated for activity

> 90% as determined by reducing SDS-PAGE.

< 10 EU/mg of the protein as determined by the LAL method

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

This product is provided as lyophilized powder which is shipped with ice packs.

Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

CCL27/CTACK, also known as CTACK, is a small cytokine belonging to the CC chemokine family. Members of this family are proteins characterized by two adjacent cysteines. CCL27/CTACK is chemotactic for skin-associated memory T lymphocytes. CCL27/CTACK may also play a role in mediating homing of lymphocytes to cutaneous sites. CCL27/CTACK plays a pivotal role in establishing the inflammatory infiltrate characteristic for common inflammatory skin diseases. Throμgh binding to the chemokine receptor 1 (CCR1), CCL27/CTACK mediates inflammation by promoting lymphocyte migration into the skin.