Recombinant Mouse PDGF-BB Protein(Sumo Tag)
- 货号：GPEM0184
Price:
| 别称 |
Sis;Pdgfb;Becaplermin;c-sis;PDGF Subunit B;PDGF2;PDGF-2;PDGFBB;Platelet-Derived Growth Factor B Chain;Platelet-Derived Growth Factor Beta Polypeptide;Platelet-Derived Growth Factor Subunit B;Proto-Oncogene c-Sis;SSV
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| 表达系统 |
E.coli
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| 序列 |
Ser82-Thr190
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| 蛋白编码 |
P31240
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| 种属 |
Mouse
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| 计算分子量 |
24.8 kDa
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| 表观分子量 |
33 kDa
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| 标签 |
N-Sumo
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| 生物活性 |
Not validated for activity
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| 纯度 |
> 90% as determined by reducing SDS-PAGE.
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| 内毒素 |
< 10 EU/mg of the protein as determined by the LAL method
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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| 复溶方法 |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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| 背景 |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor.
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027-65384716
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武汉市高新大道858号光谷生物医药产业园二期B18栋