AF/LE Purified Anti-Human CD137 Antibody[4B4-1]
![AF/LE Purified Anti-Human CD137 Antibody[4B4-1]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性： FCM
- 亚型： Mouse IgG1, κ
- 宿主： Mouse
| Alternate Names | CDw, TNFRSF, TNFRSF9, 4-1BB, CD137, CDw137, ILA, 4-1BB ligand receptor, Induced By Lymphocyte Activation, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, 4 1BB, 4 1BB ligand receptor, 4-1BB Ligand Receptor T Cell, Antigen 4-1BB Homolog, CD 137, CD137 antigen, HLDA VI, homolog of, Homolog of mouse 4 1BB, induced by lymphocyte activation (ILA), Interleukin activated receptor homolog of mouse Ly63, Ly63, MGC2172, mouse, OTTHUMP00000044294, Receptor protein 4 1BB, T cell antigen 4 1BB homolog, T cell antigen ILA, TNF receptor superfamily member 9, TNR9, Tumor necrosis factor receptor superfamily member 9 |
| Clone No | |
| Isotype | Mouse IgG1, κ |
| Leadtime |
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| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Human CD137 gene |
| Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
|
| Background |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
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| Immunogen | Recombinant Human CD137 protein |
| Abbre | CD137 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Applications | |
| Research Areas | Cell Biology;Immunology;Cancer;Stem Cells |
| Concentration | ≥ 1 mg/mL |
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12个月 |
| Shipping |
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HEK293T cells transfected with pcDNA3.1 plasmid encoding Human CD137 gene were stained with 0.2 μg AF/LE Purified Anti-Human CD137 Antibody[4B4-1] (Right) and 0.2 μg Mouse IgG1, κ Isotype Control (Left), followed by Alexa Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
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