AF/LE Purified Anti-Human CD28 Antibody[CD28.2]-Elabscience伊莱瑞特【官网】

AF/LE Purified Anti-Human CD28 Antibody[CD28.2]

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货号：E-AB-F11950
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说明书

说明书

AF/LE Purified Anti-Human CD28 Antibody[CD28.2]

Price: ¥420.00 ¥190.00

Size:

100 μg 25 μg

应用性： FCM;Activ
亚型： Mouse IgG1, κ
宿主： Mouse

Alternate Names	GPSAT, GYPA, HGpMiX, MNS, PAS2
Clone No	CD28.2
Isotype	Mouse IgG1, κ
Leadtime	咨询
Verified Samples	Verified Samples in FCM: Human peripheral blood red
Dilution	FCM 2 μg/mL(1×10⁵-5×10⁵ cells)
Background	CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
Abbre	CD28
Swissprot	P10747
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Applications	FCM;Activ
Research Areas	Costimulatory Molecules;Immunology
Concentration	≥ 1 mg/mL
Conjugation	None (AF/LE)
Storage Buffer	Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Storage	Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Expiration Date	12个月
Shipping	Ice bag

Human peripheral blood red blood cells were stained with 0.2 μg AF/LE Purified Anti-Human CD28 Antibody[CD28.2] (Right) and 0.2 μg Mouse IgG1, κ Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.

Extracellular vesicle surface display of αPD-L1 and αCD3 antibodies via engineered late domain-based scaffold to activate T-cell anti-tumor immunity

IF: 15.500

Journal： Journal of Extracellular Vesicles (2024)

DOI：10.1002/jev2.12490

Reactivity：Human
Annihilation of Non-small Cell Lung Cancer by NKG2D CAR-T Cells Produced from T Cells from Peripheral Blood of Healthy Donors

IF: 2.300

Journal： JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2023)

DOI：10.1089/jir.2023.0043

PMID：37819621

Reactivity：Human

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