AF/LE Purified Anti-Human/Mouse CD44 Antibody[IM7]
![AF/LE Purified Anti-Human/Mouse CD44 Antibody[IM7]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性： FCM
- 亚型： Rat IgG2b, κ
- 宿主： Rat
| Alternate Names | MDU2, MDU3, MIC4, CD44, CD44 antigen, CDw44, Epican, LHR, PGP-1, PGP-I, Phagocytic glycoprotein 1, Phagocytic glycoprotein I |
| Clone No | |
| Isotype | Rat IgG2b, κ |
| Leadtime |
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| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
| Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
|
| Background |
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
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| Immunogen | Recombinant Human;Mouse CD44 protein |
| Abbre | CD44 |
| Swissprot | |
| Host | Rat |
| Reactivity | Human;Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Applications | |
| Research Areas | Cell Adhesion;Cell Biology;Immunology;Stem Cells |
| Concentration | ≥ 1 mg/mL |
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12个月 |
| Shipping |
Ice bag |
C57/BL6 Mouse splenocytes were stained with 0.2 μg AF/LE Purified Anti-Human/Mouse CD44 Antibody[IM7] (Right) and 0.2 μg Rat IgG2b, κ Isotype Control (Left), followed by Alexa Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.
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EMF treatment delays mesenchymal stem cells senescence during long-term in vitro expansion by modulating autophagy
IF: 4.600Journal： Frontiers in Cell and Developmental Biology (2024)Reactivity：Rat
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