AF/LE Purified Anti-Mouse CD115/CSF-1R Antibody[AFS98]
![AF/LE Purified Anti-Mouse CD115/CSF-1R Antibody[AFS98]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性： FCM;Block;Neut
- 亚型： Rat IgG2a, κ
- 宿主： Rat
| Alternate Names | CD115, CSF-1 receptor (EC:2.7.10.1), CSF-1-R, CSF-1R, Csf1r, Csfmr, Fms, M-CSF-R, Macrophage colony-stimulating factor 1 receptor, Proto-oncogene c-Fms |
| Clone No | |
| Isotype | Rat IgG2a, κ |
| Leadtime |
咨询
|
| Background |
CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.
|
| Abbre | CD115/CSF-1R |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Applications | |
| Research Areas | Immunology |
| Concentration | ≥ 1 mg/mL |
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12个月 |
| Shipping |
Ice bag |
| E-AB-F1107A | Purified Anti-Mouse CD115/CSF-1R Antibody[AFS98] | 100 μg , 25 μg |
| E-AB-F1107D | PE Anti-Mouse CD115/CSF-1R Antibody[AFS98] | 100Tests , 50Tests , 100Tests×2 |
| E-AB-F1107E | APC Anti-Mouse CD115/CSF-1R Antibody[AFS98] | 100Tests , 50Tests , 100Tests×2 |
| E-AB-F1107UD | PE Anti-Mouse CD115/CSF-1R Antibody[AFS98] | 100μg , 25μg |
| E-AB-F1107UE | APC Anti-Mouse CD115/CSF-1R Antibody[AFS98] | 100μg , 25μg |
积分商城
微信公众号
