AF/LE Purified Anti-Mouse CD279/PD-1 Antibody[29F.1A12]
![AF/LE Purified Anti-Mouse CD279/PD-1 Antibody[29F.1A12]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性： FCM;Block;Neut
- 亚型： Rat IgG2a, κ
- 宿主： Rat
| Alternate Names | Programmed Death-1, PD-1 |
| Clone No | |
| Isotype | Rat IgG2a, κ |
| Leadtime |
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| Background |
CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
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| Abbre | CD279/PD-1 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Applications | |
| Research Areas | Cancer Biomarkers;Immunology;Inhibitory Molecules |
| Concentration | ≥ 1 mg/mL |
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12个月 |
| Shipping |
Ice bag |
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