AF/LE Purified Anti-Mouse CD62L Antibody[MEL-14]
![AF/LE Purified Anti-Mouse CD62L Antibody[MEL-14]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性: FCM;Neut
- 亚型: Rat IgG2a, κ
- 宿主: Rat
Alternate Names | CD62L, CD62 antigen-like family member L, L-selectin, LAM-1, LECAM1, Lnhr, Ly-22, Ly22, Lymph node homing receptor, Sell |
Clone No | |
Isotype | Rat IgG2a, κ |
Leadtime |
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Verified Samples | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
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Background |
CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.
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Abbre | CD62L |
Swissprot | |
Host | Rat |
Reactivity | Mouse |
Clonality | Monoclonal |
Applications | |
Research Areas | Cell Adhesion;Cell Biology;Costimulatory Molecules;Immunology;Innate Immunity |
Concentration | ≥ 1 mg/mL |
Conjugation | None (AF/LE) |
Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
Expiration Date | 12个月 |
Shipping |
Ice bag |
C57/BL6 Mouse splenocytes were stained with 0.2 μg AF/LE Purified Anti-Mouse CD62L Antibody[MEL-14] (Right) and 0.2 μg Rat IgG2a, κ Isotype Control (Left), followed by FITC-conjugated Goat Anti-Rat IgG Secondary Antibody.