AF/LE Purified Anti-Mouse CD80 Antibody[16-10A1]
![AF/LE Purified Anti-Mouse CD80 Antibody[16-10A1]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性: FCM;Block
- 亚型: Armenian Hamster IgG
- 宿主: Armenian Hamster
Alternate Names | Activation B7-1 antigen, B7, Cd80, T-lymphocyte activation antigen CD80 |
Clone No | |
Isotype | Armenian Hamster IgG |
Leadtime |
咨询
|
Background |
CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
|
Abbre | CD80 |
Swissprot | |
Host | Armenian Hamster |
Reactivity | Mouse |
Clonality | Monoclonal |
Applications | |
Research Areas | Cell Biology;Costimulatory Molecules;Immunology;Neuroscience;Neuroscience Cell Markers |
Concentration | ≥ 1 mg/mL |
Conjugation | None (AF/LE) |
Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
Expiration Date | 12个月 |
Shipping |
Ice bag |