AF/LE Purified Anti-Mouse TCR γ/δ Antibody[UC7-13D5]
![AF/LE Purified Anti-Mouse TCR γ/δ Antibody[UC7-13D5]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性: FCM
- 亚型: Armenian Hamster IgG
- 宿主: Armenian Hamster
Alternate Names | γ/δ TCR, TCR-γ/δ |
Clone No | |
Isotype | Armenian Hamster IgG |
Leadtime |
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Background |
T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR γ/δ associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR γ/δ have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-γ/δ-bearing T cells in vitro, and to deplete peripheral TCR-γ/δ-bearing T cells in vivo.
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Abbre | TCR γ/δ |
Host | Armenian Hamster |
Reactivity | Mouse |
Clonality | Monoclonal |
Applications | |
Research Areas | Adaptive Immunity;Immunology |
Concentration | ≥ 1 mg/mL |
Conjugation | None (AF/LE) |
Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
Expiration Date | 12个月 |
Shipping |
Ice bag |
E-AB-F1124A | Purified Anti-Mouse TCR γ/δ Antibody[UC7-13D5] | 100 μg , 25 μg |