Carbonic anhydrases ( CAs ) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes , including respiration , calcification , acid-base balance , bone resorption , and the formation of aqueous humor , cerebrospinal fluid , saliva , and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma , but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation.

CAIX;CA-IX;MN;Carbonic Dehydratase;RCC-Associated Protein G250

Human

PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5

-20℃

12个月