Human CASP3 Antibody Pair Set

Price:
Size:
50 μL & 100 μg
- 反应性: Human
Background |
This gene encodes a protein which is a member of the cysteine-aspartic acid protease ( caspase ) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits , large and small , that dimerize to form the active enzyme. This protein cleaves and activates caspases 6 , 7 and 9 , and the protein itself is processed by caspases 8 , 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein , which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
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Synonyms |
CPP32;CPP32B;SCA-1;Apoptain;Yama
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Swissprot | |
Reactivity |
Human
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Buffer |
PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5
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Storage |
-20℃
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Expiration date |
12个月
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