The protein encoded by this gene associates with class II major histocompatibility complex ( MHC ) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor ( MIF ) which , when bound to the encoded protein , initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein ( APP ) and suppresses the production of amyloid beta ( Abeta ) . Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

CD74;DHLAG;HLADG;II;Ia-GAMMA;CD74 molecule

Human

PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5

-20℃

12个月