Human EGFR Antibody Pair Set
Price:
Size:
50 μL & 100 μg
- 反应性： Human
| Background |
EGFR,also named as ERBB1,is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12,encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression,including cell proliferation,apoptosis,angiogenesis,and metastatic spread. Mutations in this gene are associated with lung cancer.
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| Synonyms |
EGFR;ERBB;ERBB1;HER1;NISBD2;PIG61;mENA;
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human EGFR in ELISAs
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| Buffer |
Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
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| Storage |
-20℃
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| Expiration date |
12个月
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