Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family , such as activin , BMP2 and MSTN. Inhibits activin A- , activin B- , BMP2- and MSDT-induced cellular signaling , more effective on activin A than on activin B. Involved in bone formation , inhibits osteoclast differentiation. Involved in hematopoiesis , involved in differentiation of hemopoietic progenitor cells , increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10.

FSTL3;FSRP;Follistatin-Related Protein;Follistatin Like 3;Follistatin-Like 3 ( Secreted Glycoprotein );Follistatin-Related Protein 3

Human

PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5

-20℃

12个月