This gene encodes a member of the small heat shock protein ( HSP20 ) family of proteins. In response to environmental stress , the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers , and the encoded protein may promote cancer cell proliferation and metastasis , while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.

HSPB1;CMT2F;HMN2B;HS.76067;HSP27;HSP28;Hsp25;SRP27

Human

PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5

-20℃

12个月