The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant , a modulator of T cell activation , and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing , which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide , while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.

IL16;LCF;NIL16;PRIL16;PrIL-16

Human

PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5

-20℃

12个月