The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13 , which may contribute to many overlapping functions of this cytokine and IL13. STAT6 , a signal transducer and activator of transcription , has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene , IL3 , IL5 , IL13 , and CSF2 form a cytokine gene cluster on chromosome 5q , with this gene particularly close to IL13. This gene , IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

IL4;BCGF-1;BCGF1;BSF-1;BSF1

Human

PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5

-20℃

12个月