This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation , maturation , recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor , which is a heterodimer , whose beta subunit is shared with the receptors for interleukine 3 ( IL3 ) and colony stimulating factor 2 ( CSF2/GM-CSF ) . This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 ( IL4 ) , interleukin 13 ( IL13 ) , and CSF2 . This gene , IL4 , and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

IL5;EDF;TRF;E-CSF;ESGF

Human

PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5

-20℃

12个月