Proteins of the matrix metalloproteinase ( MMP ) family are involved in the breakdown of extracellular matrix in normal physiological processes , such as embryonic development , reproduction , and tissue remodeling , as well as in disease processes , such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans , fibronectin , elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing , and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

MMP7;MPSL1;PUMP-1;Matrilysin

Human

PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5

-20℃

12个月