Neuropilin-1 (NRP1) is a transmembrane glycoprotein expressed by endothelial,dendritic,and regulatory T cells,as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor,involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis,axon guidance,cell survival,migration,and invasion.

BDCA4;CD304;NP1;NRP;VEGF165R;Neuropilin-1;NRP1;BDCA-4;DKFZp686A03134;DKFZp781F1414;Neuropilin1;CD304 antigen;neuropilin 1;Vascular endothelial cell growth factor 165 receptor

Human

Detects Human NRP1 in ELISAs

Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4

-20℃

12个月