Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release;vasoconstriction , and increase in blood pressure. Renin , an aspartyl protease , cleaves angiotensinogen to form angiotensin I , which is converted to angiotensin II by angiotensin I converting enzyme , an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described , but their full-length nature has not been determined.

Angiotensinogenase

Human

PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5

-20℃

12个月