Human SOST Antibody Pair Set
Price:
Size:
50 μL & 100 μg
- 反应性： Human
| Background |
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like ( CTCK ) domain and sequence similarity to the DAN ( differential screening-selected gene aberrative in neuroblastoma ) family of bone morphogenetic protein ( BMP ) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder , sclerosteosis , which causes progressive bone overgrowth. A deletion downstream of this gene , which causes reduced sclerostin expression , is associated with a milder form of the disorder called van Buchem disease.
|
| Synonyms |
CDD;VBCH
|
| Swissprot | |
| Reactivity |
Human
|
| Buffer |
PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5
|
| Storage |
-20℃
|
| Expiration date |
12个月
|
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