LT-α,also known as TNF-β,is a potent mediator of inflammatory and immune responses.   It belongs to the TNF superfamily of ligands and signals through TNFR1 and TNFR2.   LT-α is produced by activated T and B lymphocytes,and has similar activities to TNF-α.   Like TNF-α,LT-α (TNF-β) is involved in the regulation of various biological processes including cell proliferation,differentiation,apoptosis,lipid metabolism,coagulation,and neurotransmission.   LT-α is secreted as a soluble polypeptide,but can form heterotrimers with LT-β,which effectively anchors the LT-α to the cell surface.   LT-α is cytotoxic to a wide range of tumor cells.

LT;LTA;TNFB;TNFSF1;TNF Superfamily;Member 1;Lymphotoxin Alpha

Human

Detects Human TNF-β in ELISAs

Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4

-20℃

12个月