The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin , as well as alpha-1 protease inhibitor , a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes , including myofibril necrosis in myopathies and in myocardial ischemia , and in the renal tubular response to proteinuria. This protein , which is a member of the peptidase C1 family , is a dimer composed of disulfide-linked heavy and light chains , both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.

CTSL1;CATL;MEP

Monkey

PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5

-20℃

12个月