alpha-Fetoprotein ( AFP ) ;is albuminoid superfamily protein that is synthesized in the fetus primarily by the liver;yolk sac;and tissues of gastrointestinal origin. It is one of the earliest markers of the hepatocyte lineage. AFP acts as a carrier protein for steroids;bilirubin;fatty acids;retinoids;and flavonoids. In addition;it can exert immunosuppressive activity;regulate cell proliferation and apoptosis;initiate intracellular signaling;and contribute to cell invasion. Altered levels of both fetal and maternal AFP have been associated with hypothyroidism;autoimmune disorders;and heart defects. Low maternal serum AFP levels are associated with a higher incidence of Down syndrome;whereas higher levels are associated with spina bifida and anencephaly. Elevated AFP levels are also coincident with liver;stomach;and germ cell cancers.

AFP;FETA;HPAFP;Alpha-fetoglobulin;oralpha fetal protein

Monkey

PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5

-20℃

12个月