Acetylcholinesterase (ACHE) is a member of the alpha/beta hydro lase superfamily.    It is a serine hydrolase with a carboxyl esterase activity.    Its main function is to terminate transmission at cholinergic synapses by hydrolyzing the neurotransmitter acetylcholine (ACH).    Its inhibitors,such as donepezil,rivastigmine,and galantamine,have been approved to treat mild-to-moderate Alzheimer's disease and other dementia.    Although ACHE is an essential enzyme primarily expressed in the central and peripheral nervous systems,its expression has been observed in various cell types including fibroblasts,osteoblasts,erythrocytes,vascular endothelial cells,and leukocytes.    In addition to the main function,its role includes neurogenesis,neurodegeneration,apoptotic sensitivity,cellular proliferation and differentiation,and a possible role on tumorigenesis.

ACEE;ARACHE;N-ACHE

Mouse

Detects Mouse AChE in ELISAs

Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4

-20℃

12个月