The protein encoded by this gene is a member of the fibroblast growth factor ( FGF ) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes , such as limb and nervous system development , wound healing , and tumor growth. The mRNA for this gene contains multiple polyadenylation sites , and is alternatively translated from non-AUG ( CUG ) and AUG initiation codons , resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect , whereas , the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

FGF-2;B-FGF;BFGF;FGFB;HBGF-2;prostatropin;heparin-binding growth factor 2

Mouse

PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5

-20℃

12个月