CD66a,known as carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM-1),is a glycoprotein of the immunoglobulin superfamily and the carcinoembryonic antigen family.  CEACAM-1 functions as an intercellular adhesion molecule,an angiogenic factor,and a tumor cell growth inhibitor.  CEACAM-1 is expressed in multiple epithelial malignancies,including gastric cancer,colorectal cancer,and pancreatic cancer,as well as in NSC lung cancer and melanoma.  CEACAM-1 comprises one N-terminal variable domain,six C2-like Ig domains and glycosylphosphatidylinositol (GPI) linker,which facilitate adhesion through homophilic and/or heterophilic (CEACAM1–CEACAM5) interactions.  CEACAM-1 has a significant clinical role as a tumor marker for several tumors including gastrointestinal and respiratory malignancies.  CEACAM-1 has variable roles in tumor initiation,progression,and metastasis.

CEACAM-1;CEACAM1;CD66a;CEA;Meconium antigen 100

Mouse

Detects Mouse CEACAM1 in ELISAs

Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4

-20℃

12个月