Galectin-3 is a member of the lectin family,which includes 15 mammalian lectin members.    Like all galectins,galectin-3 contains a carbohydrate recognition binding domain of about 130 amino acids that enables the specific binding of β-galactosides.    This protein has been shown to be involved in cell adhesion,cell activation,chemoattraction,cell growth and differentiation,cell cycle,and apoptosis.    Galectin-3 induces pro-inflammatory cytokines and inhibits Th2 type cytokine production.    It chemoattracts monocytes and macrophages,and activates and degranulates basophils and mast cells.    Galectin-3 has been shown to be involved in cancer,inflammation,fibrosis,heart disease,and stroke.    It has also been shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure,including myofibroblast proliferation,tissue repair,inflammation,fibrogenesis,and ventricular remodeling.    In addition,galectin-3 was found to contribute to tumor cell evasion of the immune system.    Galectin-3 is increasingly being used as a diagnostic marker for different cancers.    It can be screened for and used as a prognostic factor to predict the progression of the cancer.

LGALS3;CBP35;GALBP;GALIG;L31;LGALS2;MAC2;Lectin;Galactoside-Binding Soluble 3

Mouse

Detects Mouse GAL3 in ELISAs

Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4

-20℃

12个月