Cytokine that can act as a growth factor for activated T and NK cells , enhance the lytic activity of NK/lymphokine-activated killer cells , and stimulate the production of IFN-gamma by resting PBMC.Associates with IL23A to form the IL-23 interleukin , a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R , activates the Jak-Stat signaling cascade , stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

IL-23A;IL23P19;P19;SGRF

Mouse

PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5; PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5

-20℃

12个月