CD80 is a 60 kD highly glycosylated protein.  It is a member of the Ig superfamily and is also known as B7-1,B7,and Ly-53.  CD80 is constitutively expressed on dendritic cells and monocytes/macrophages,and inducibly expressed on activated B and T cells.  The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells,macrophages,and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation,proliferation,and cytokine production.  CD80 appears to be expressed later in the immune response than CD86.  CD80 can also bind to CD152,also known as CTLA-4,to deliver an inhibitory signal to T cells.

CD80;CD28LG;CD28LG1;BB1;B7-1 Antigen;T-lymphocyte activation antigen CD80;CTLA-4 counter-receptor B7.1

Mouse

Detects Mouse LAB7-1 in ELISAs

Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4

-20℃

12个月