L-selectin,belonging to the selectin/LECAM family,is a type I transmembrane protein,consisted of one C-type lectin domain and EGF-like repeats,followed by a transmembrane region and a short cytoplasmic tail of 17 amino acids.   L-selectin is constitutively expressed on leukocytes.    As a homing receptor,L-selectin mediates adhesion and rolling of leukocytes on endothelial cells,in turn leukocytes enter peripheral lymphoid organs via high endothelial venules (HEV).    L-selectin also directs leukocytes to inflammation sites.    Circulating leukocytes can also tether on adherent leukocytes through the interaction between L-selectin and P-selectin glycoprotein ligand-1 (PSGL-1).    L-selectin also interacts with mucins,such as CD34,glycosylated cell adhesion molecule-1 (GlyCAM-1) and podocalyxin.

CD62L;LAM1;LAM-1;LECAM1;Leu-8;LEU8;LNHR;LSEL;Lyam-1;LYAM1;PLNHR;TQ1

Mouse

Detects Mouse SELL in ELISAs

Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4

-20℃

12个月