Purified Anti-Human CD146 Antibody[AA98]
![Purified Anti-Human CD146 Antibody[AA98]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性： FCM
- 亚型： Mouse IgG2a, κ
- 宿主： Mouse
| Alternate Names | MUC, cell surface glycoprotein MUC, MCAM, CD146, MUC18, cell surface glycoprotein MUC18, S-endo, MCAM, Mel-CAM, Endo-CAM, CD146, cell surface glycoprotein MUC18, MUC18, A32 antigen, CD 146, CD146 antigen, Cell surface glycoprotein P1H12, Gicerin, Melanoma adhesion molecule, Melanoma associated antigen A32, Melanoma associated antigen MUC18, Melanoma associated glycoprotein MUC18, melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MelCAM, MUC 18, S endo 1, S endo 1 endothelial associated antigen, S-endo 1 endothelial-associated antigen |
| Clone No | |
| Isotype | Mouse IgG2a, κ |
| Leadtime |
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| Verified Samples | Verified Samples in FCM: Hela |
| Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
|
| Background |
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
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| Immunogen | Recombinant Human CD146 protein |
| Abbre | CD146 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Applications | |
| Research Areas | Immunology;Signal Transduction;Cancer;Stem Cells;Cardiovascular |
| Concentration | ≥ 1 mg/mL |
| Conjugation | Unconjugated |
| Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12个月 |
| Shipping |
Ice bag |
Hela were stained with 0.2 μg Purified Anti-Human CD146 Antibody[AA98] (Right) and 0.2 μg Mouse IgG2a, κ Isotype Control (Left), followed by Alexa Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
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