Purified Anti-Human CD180 Antibody[G28-8]
![Purified Anti-Human CD180 Antibody[G28-8]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性: FCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Alternate Names | LY64, RP105, CD180, Ly78 |
Clone No | |
Isotype | Mouse IgG1, κ |
Leadtime |
咨询
|
Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
|
Background |
CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.
|
Immunogen | Recombinant Human CD180 protein |
Abbre | CD180 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Purification Method | >98%, Protein A/G purified |
Applications | |
Research Areas | Immunology;Microbiology |
Concentration | ≥ 1 mg/mL |
Conjugation | Unconjugated |
Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12个月 |
Shipping |
Ice bag |
Human peripheral blood lymphocytes were stained with 0.2 μg Purified Anti-Human CD180 Antibody[G28-8] (Right) and 0.2 μg Mouse IgG1, κ Isotype Control (Left), followed by Alexa Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody, then anti-Human CD19 FITC-conjugated Monoclonal Antibody.