Purified Anti-Human CD195 Antibody[RoAb13]
![Purified Anti-Human CD195 Antibody[RoAb13]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性: FCM
- 亚型: Mouse IgG2a, κ
- 宿主: Mouse
Alternate Names | IDDM, CCCKR, CMKBR, CC-CKR, CKR, CCR, CKR5, CCR-5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5, CCR5, CCCKR5, CC-CKR-5, CCR-5, CD195, CKR-5, CMKBR5, IDDM22 |
Clone No | |
Isotype | Mouse IgG2a, κ |
Leadtime |
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Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
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Background |
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles; the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene.
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Immunogen | Recombinant Human CD195 protein |
Abbre | CD195 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Purification Method | >98%, Protein A/G purified |
Applications | |
Research Areas | Neuroscience;Immunology;Microbiology;Signal Transduction;Cancer;Cardiovascular |
Concentration | ≥ 1 mg/mL |
Conjugation | Unconjugated |
Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12个月 |
Shipping |
Ice bag |
Human peripheral blood lymphocytes were stained with 0.2 μg Purified Anti-Human CD195 Antibody[RoAb13] (Right) and 0.2 μg Mouse IgG2a, κ Isotype Control (Left), followed by Alexa Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.