Purified Anti-Human CD32 Antibody[IV-3]
![Purified Anti-Human CD32 Antibody[IV-3]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性: FCM;Block
- 亚型: Mouse IgG2b, κ
- 宿主: Mouse
Alternate Names | IGFR2, CD32, CDw32, FCG2, FCGR2B, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, IgG Fc receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-b |
Clone No | |
Isotype | Mouse IgG2b, κ |
Leadtime |
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Verified Samples | Verified Samples in FCM: Human peripheral blood granulocyte |
Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
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Background |
CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).
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Immunogen | Recombinant Human CD32 protein |
Abbre | CD32 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Purification Method | >98%, Protein A/G purified |
Applications | |
Research Areas | Immunology;Innate Immunity |
Concentration | ≥ 1 mg/mL |
Conjugation | Unconjugated |
Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12个月 |
Shipping |
Ice bag |
Human peripheral blood granulocyte were stained with 0.2 μg Purified Anti-Human CD32 Antibody[IV-3] (Right) and 0.2 μg Mouse IgG2b, κ Isotype Control (Left), followed by Alexa Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
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