Purified Anti-Human CD3 Antibody[OKT-3]-Elabscience伊莱瑞特【官网】

Purified Anti-Human CD3 Antibody[OKT-3]

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货号：E-AB-F1001A
文献（2）
说明书

说明书

Price: ¥400.00 ¥180.00

Size:

100 μg 25 μg

应用性： FCM
亚型： Mouse IgG2a, κ
宿主： Mouse

Alternate Names	CD3E, CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E
Clone No	OKT3
Isotype	Mouse IgG2a, κ
Leadtime	咨询
Verified Samples	Verified Samples in FCM: Human peripheral blood lymphocytes
Dilution	FCM 2 μg/mL(1×10⁵-5×10⁵ cells)
Background	CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.
Immunogen	Recombinant Human CD3 protein
Abbre	CD3
Swissprot	P07766
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Purification Method	>98%, Protein A/G purified
Applications	FCM
Research Areas	Immunology
Concentration	≥ 1 mg/mL
Conjugation	Unconjugated
Storage Buffer	PBS, pH 7.2. Contains 0.05% proclin 300.
Storage	Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Expiration Date	12个月
Shipping	Ice bag

Human peripheral blood lymphocytes were stained with 0.2 μg Purified Anti-Human CD3 Antibody[OKT-3](Right) and 0.2 μg Mouse IgG2a, κ Isotype Control(Left), followed by PE-conjugated Goat Anti-Mouse IgG Secondary Antibody.

Blocking the PD-1 signal transduction by occupying the phosphorylated ITSM recognition site of SHP-2

IF: 8.000

Journal： Science China-Life Sciences (2024)

DOI：10.1007/s11427-024-2706-2

Reactivity：Human
Annihilation of Non-small Cell Lung Cancer by NKG2D CAR-T Cells Produced from T Cells from Peripheral Blood of Healthy Donors

IF: 2.300

Journal： JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2023)

DOI：10.1089/jir.2023.0043

PMID：37819621

Reactivity：Human

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