Purified Anti-Human CD3E Antibody[CRIS-7]
![Purified Anti-Human CD3E Antibody[CRIS-7]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性： FCM
- 亚型： Mouse IgG2a, κ
- 宿主： Mouse
| Alternate Names | IMD, CD3E, IMD18, T3E, TCRE, CD3e molecule, CD3 epsilon, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, T3, CD_antigen: CD3e, epsilon |
| Clone No | |
| Isotype | Mouse IgG2a, κ |
| Leadtime |
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| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
|
| Background |
The CD3ε chain of the CD3-TCR complex is a type I membrane protein that undergoes conformational change following ligation of the TCR-CD3 complex. This conformational change leads to exposure of the proline rich sequence in CD3ε and results in recruitment of Nck. It is expressed by all mature T cells and forms a heteromeric complex with CD3 α/β or γ/δ and ζ chains. It is important in T cell development, and deficiency of this gene has been associated with severe immunodeficiency.
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| Immunogen | Recombinant Human CD3E protein |
| Abbre | CD3E |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Applications | |
| Research Areas | Immunology;Stem Cells |
| Concentration | ≥ 1 mg/mL |
| Conjugation | Unconjugated |
| Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12个月 |
| Shipping |
Ice bag |
Human peripheral blood lymphocytes were stained with 0.2μg Purified Anti-Human CD3E Antibody[CRIS-7] (Right) and 0.2μg mouse IgG2a,κ lsotype Control (Left), followed by AF647-conjugated goat Anti-mouse IgG Secondary Antibody.
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