Purified Anti-Human CD47 Antibody[CC2C6D4]
![Purified Anti-Human CD47 Antibody[CC2C6D4]](http://files.elabscience.cn/assets/images/loading.png)
Price:
Size:
100 μg
25 μg
- 应用性: FCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Alternate Names | Cd47, IAP, Integrin-associated protein, Leukocyte surface antigen CD47 |
Clone No | |
Isotype | Mouse IgG1, κ |
Leadtime |
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Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
Dilution |
FCM 2 μg/mL(1×105-5×105 cells)
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Background |
CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.
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Abbre | CD47 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Applications | |
Research Areas | Immunology;Innate Immunity |
Concentration | ≥ 1 mg/mL |
Conjugation | Unconjugated |
Storage Buffer | PBS, pH 7.2. Contains 0.05% proclin 300. |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Expiration Date | 12个月 |
Shipping |
Ice bag |
Human peripheral blood lymphocytes were stained with 0.2 μg Purified Anti-Human CD47 Antibody[CC2C6D4] (Right) and 0.2 μg Mouse IgG1, κ Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.